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Monday, February 07, 2005
Update on Dave Eastman
Hello everyone,
Many
have been waiting for the nine-month update on David
Eastman, the fellow who was told he would be dead
from his glioblastoma brain tumor in 12 months. As
you will see, his health is the envy of most of the
people who meet him. In fact, a friend whom he has
known for a lot of years met Dave the other day, and
not having seen him for quite a while, could not
believe he could be so well!
Enjoy the story. Share it as widely
as you wish/can. Just keep in mind that it cannot be
used to promote any company or commercial products.
That's why no mention is being made of any company
or products anywhere in this e-mail. When you share
the story in any form you must do the same. (What
you say verbally is your own concern, if you know
what I mean.)
This is going out to hundreds
of people, who in turn will forward it. Dave and
Deb don't mind answering enquiries from those
with serious health challenges, but please
protect them from being inundated with phone
calls. Thank you for being considerate of them.
The most important information is the protocol
of Dr. Reg
McDaniel's protocol (below).
PS Expect a further update when Dave has completed
his first year, in April '05.
My
name is David Eastman. I am enjoying a great
recovery from a deadly glioblastoma brain tumor.
It's 'medically impossible,' but it's actually
happening, and I want to share the reason with the
whole world.
Nine
months ago I was told I had only 12 months to live,
yet a few days ago my oncologist reported that I am
in total recovery, in great general health
and there's no sign of cancer anywhere in my
body! My six month report was excellent, but this
one is even better. I'm not greatly surprised, but I
sure am delighted! My oncologist is, too. Cancer
people don't get to deal with many success stories.
I
feel healthier than any time in my entire life. My
body has actually gone through a total renewal and I
have a whole new outlook on life. I am grateful to
God for excellent medical care, but I am
extremely grateful for the gift of
glyconutritionals* that make all the difference. I
am very healthy and very, very happy. And now I am
reaching out to others.
My
wife, Deborah, and I live near the village of Arkona,
in Southwestern Ontario, Canada. I'm 47 and a
building contractor by trade. I've always enjoyed
work and have rarely been sick. I'm back to working
as hard as ever, but my focus has shifted. Deb and I
are trying to introduce glyconutritionals to
everyone, knowing everyone needs them. We especially
try to reach cancer people. And we're succeeding!
A
whole new chapter in my life began in 1997 when good
friends Eugene and Gloria Fox told Deb and me about
some natural supplements they were taking. I was
somewhat interested, but it got Deb's attention
because of her severe allergies. So we registered to
receive the products, and they really worked! Deb
was soon much better and never wanted to be without
the products. As for me, I was convinced I was
healthy so I hardly touched them. That was almost a
fatal mistake! Now I know that feeling healthy
doesn't have much to do with whether you are really
well. That can be very misleading and it certainly
fooled me.
Everything changed in the spring of 2004 when I was
struck down by terrible headaches and then diagnosed
with a glioblastoma brain tumor. The cancer expert
told Deb, "It will kill him. In spite of all
we can do the tumor will grow back -- and he
will die within 12 months. This will happen."
He was so sure because no one escapes that kind of
brain tumor. Just about everyone dies within 12
months. I'm told it's as lethal as pancreatic
cancer.
The
surgeon said he would remove as much of the tumor as
possible, but didn't expect to get it all. That's
because the roots went right into my brain. Trying
to get it all would have killed me. The surgery was
performed in London, Ontario, Canada, a world-class
medical and research center.
Deb
and I put everything in the hands of the Lord, along
with our praying friends. I was not afraid because
the Lord is very real to us and has seen us through
many problems, with this being just one more. It
also helped that for seven years we learned how very
effective
glyconutritionals are.
When
I came out of the anesthetic the Lord almost spoke
audibly to me: "Eugene and Gloria will come
alongside you." We soon found out what that meant.
They introduced us to the cancer protocol of Dr. Reg
McDaniel, a pioneer in
glyconutritional technology who has been working
with it for the last 20 years. I got on the protocol
right away and intend to stay on it for the five
years recommended by Dr. Reg.
A
hero of ours is Dr. Rayburne Goen, M.D., who
discovered glyconutritionals at age 85, after 60
years of medical practice. He says, "Without an
adequate supply of these vital nutrients the body is
dysfunctional, sick, dying or dead." Exactly right.
We
will share this technology that saved my life with
anyone. It can open up a quality of life most of us
never thought possible, the quality of life we are
enjoying.
We're planning a big celebration after I complete
what was supposed to be the last year of my life,
completing it in great health. We'll announce the
details later.
Summary of My Experience
The
first sign that something was wrong was a series of very
severe headaches. By 25 March, 2004 Dave needed to take
large quantities of Tylenol. Here are the subsequent
events:
April 8/04 - Dave had a very difficult day at work. By
evening he could not feed himself and could not chew
food. He couldn't so much as hold a glass of water.
Light made his eyes hurt.
April 10/04 - Dave's right ear pained and seemed to be
infected. Later it was learned that the tumor was
putting pressure on that area.
April 12/04- A CAT scan
revealed the massive brain tumor.
April 15/04 - Dave had an MRI (Magnetic Resonance
Image). The tumor measured 6.5 cm X 5 cm (2.5" X 2").
That's huge!
April 16/04 - Emergency surgery for 4 1/2 hours. Dave
and Deb had been cautioned that the outcome could be
paralysis, loss of vision, a stroke, even death.
To give Dave the best chance of a good outcome Deb had
fed him large amounts of glyconutrients (the complex of
eight functional sugars listed in the medical text
Harper's Biochemistry, 26th edition, Murray et al).
She avoided difficulties of giving something to Dave by
just 'not bothering' to tell the hospital staff. She's a
nurse so it worked. That gave Dave excellent nutritional
support.
The day after the surgery Dave was sitting on the side
of his bed, waiting for breakfast, instead of being
totally bedridden as expected. Later, he went for a walk
with his twin brother, Don.
The surgeon told Dave he had been able to remove more of
the tumor than expected. There were, however, vision
problems caused by the tumor. Dave was told he would
never drive again. On 3 June, part of his remarkable
recovery was being cleared to drive again, one month
after surgery!
April 19/04 - Two days after surgery Dave was discharged
from hospital and went home. He was told he could have
been released the previous day! Prior to the surgery he
was told he would be hospitalized for weeks.
Two doctors remarked on the rapid healing of the
incision, which is now just a fine line. Deborah helped
this healing with repeated applications of a highly
concentrated glyconutritional jell.
May 5/04 - Dave began radiation therapy as an
outpatient. He also began taking a very toxic
chemotherapy agent. He received the radiation five days
a week, until 17 June. He was never sick! The pharmacist
dispensing the chemotherapy drug was amazed. Knowing how
very toxic the drug was, he phoned the Eastmans to check
on Dave. He could hardly believe what he heard. Cooking
smells bothered him a bit, but that was all. (After the
nine-month examination the chemotherapy was
discontinued.)
Through his sickness Dave lost 15 pounds. Being quite
slim already, this was serious. Soon after the surgery,
in spite of the radiation and chemotherapy, he developed
a ravenous appetite, and quickly regained the
lost weight. He says that for a while he "ate all day
long," gaining about a pound a day! He soon looked the
picture of health, and still does.
Dave and Deb had been cautioned that the chemotherapy
would drastically affect Dave's immune system, requiring
them to do everything possible to avoid him becoming
sick. But not long after coming home others in the
household became sick. Dave did not. The reason was soon
evident. His blood work, done every week, showed his
immune system as completely normal throughout his
entire recovery. A doctor remarked, "You have a very
strong immune system!" Dave and Deb just nodded and
smiled.
All Dave's vital signs have been consistently excellent,
in spite of the radiation and chemotherapy. Surely this
is only attributable to the support of the
glyconutritionals.
May 11/04 - Dave bicycled 2 1/2 miles to town to visit
his mother. He experienced no particular tiredness.
May 13/04 - Dave walked to town at a casual pace,
enjoying the exercise. He also did what he calls 'power
walks'.
May 31/04 - Dave discovered that his chronic (and quite
severe) gluten allergy had cleared up! He accidentally
ate several muffins made with wheat flour with no
reaction. Previously he would break out with serious
skin problems if he ate anything containing gluten. A
mild problem with gluten has since returned.
June 6/04 - A community benefit dinner was held for the
Eastman's, attended by 250 friends and family members.
It raised over $4,000. In his response Dave said, "I've
never felt better in my life!"
June 17/04 - CAT scan showed no evidence of the
tumor.
June 18/04 - Dave and Deb attended a family wedding and
reception. Dave experienced no particular weariness.
June 29/04 - Dave has always been active and used to hard
work so he became bored and went back to work. His first
project? Building a concrete block wall! He had none of
his old back problems. He worked full days, getting
normally tired at the end of the day, but that's all.
July 7/04 - MRI showed no sign of any tumor.
(Please remember, the Eastmans had been told
emphatically that the tumor would grow back and
kill him in 12 months. But there was no evidence
of anything of the sort.)
July 9/04 - Deb and others had been concerned about
Dave's 'vacant stare,' even though he was mentally
alert. On this day it ceased and has not returned. He
has rapidly regained any lost mental acuity and is now
reading voraciously.
At the time Deborah's
comment was, "All Dave's deficits were minor."
Dave and Deb want everyone to know that they are
convinced it's the science-based glyconutritional
technology that has restored Dave's health, along with
the radiation and chemotherapy, with everything
supported by much prayer.
October 22/04 - Follow-up MRI indicated everything is
better than ever. No sign of the tumor. Dave's blood
work continued totally normal. Every indication of
continued very good health. Dave continuing with
the glyconutritional protocol and also the chemotherapy.
Blood work now reduced to twice per month, with
follow-up MRIs to come at 9 month and 12 months after
surgery.
What is discussed here is very advanced nutritional
science --Glycobiology. Understandably, it is rapidly
becoming obvious that it is the hope of modern health
care. MIT (Massachusetts Institute of Technology)
thoroughly examined it and has publicly affirmed that
this approach to wellness will change the entire world
as we now know it.
Dave enjoying working full
days, doing physically demanding work. Nothing but a
steady, sustained recovery to full, robust health.
Outlook very positive.
This is anything but
unique. Numerous others have followed this integrative
approach to wellness with similar excellent outcomes.
Some are now cancer-free for 18 years. Recent research
indicates that a trillion or more adult stem cells are
generated by a person's own bone marrow when supported
by the glyconutrients. These cells contribute to the
restoration of the body, including the brain. This
likely explains the remarkable recoveries enjoyed by
Dave and others.
January 25/05 - All indications confirm Dave's excellent
health. The oncologist remarked that the MRI showed the
former tumor site is "even better than before."
Please
note:
What is discussed here is very advanced
nutritional science --Glycobiology. Understandably, it
is rapidly becoming obvious that it is the hope of
modern health care. MIT (Massachusetts Institute of
Technology) thoroughly examined it and has publicly
affirmed that this approach to wellness will change the
entire world as we now know it. However, these are food
supplements. They do not diagnose, mitigate or cure any
disease, but supply the body with vital, missing
nutrients so that the body can heal and care for
itself. They do not replace the care of a physician.
For more information,
contact the person who gave you this.
Thanks for your time. Feel free to contact Deborah and
me.
Sincerely,
David Eastman
8721 Birnam
Line (RR #1)
Arkona, ON,
Canada N0M 1B0
January, 2005
* Glyconutritionals are nutrients that are
science-based. They make up (supplement) nutrients
missing from the modern diet. They are vitally important
with a proven track record of supporting wellness in
outstanding ways. My experience is a classic example of
that.
Note:
The 12 month update on David Eastman was about the same, his
health is good and not trace of the tumor or cancer has been found in his body.
Friday, February 04, 2005
Biochemistry and
Molecular Biology
Note:
The OU School of Medicine puts
out a publication twice a year and it is sent to
alumni and friends of the OU School of Medicine.
This is a copy of the most recent article, Fall
of 2004.
Move over
genomics. Out of the way, proteomics. Make room
for
glycomics, the third leg of the race to
understand the body's most basic mechanisms.
Glycomics may not yet have the notoriety of its
scientific siblings, but the international
effort to identify, catalog and understand the
staggeringly complicated assemblages of sugar
molecules decorating the body's cells may wind
up being the most difficult - if not the most
important - challenge of all.
Where there are "only" about 30,000 human genes,
there are likely far more then 30 million
complex carbohydrates structures. As science is
now discovering, each may have its own critical
biological function far beyond the long-held
view that their primary purpose were for energy
storage (as glycogen) or structural (as in
connective tissue, fluid in the eye or the
exoskeletons of insects and shellfish).
Only in recent
years has the idea been widely accepted that
chemical messages between cells are encoded
within complex carbohydrates. These are large
molecules of complex carbohydrates. These are
the large molecules of sugars, assembled in
strings and branches like elaborate pendants,
which are attached to proteins and lipids. In
other words, when cells communicate chemically
with each other about everything that happens in
our bodies, from making new tissues to fighting
infection, they often say it with sugar.
Leaders in the international effort to create a
"library" of the intricate and often transitory
structures and to understand their function are
a determined group of OU College of medicine
biochemists. What these scientists have already
learned may hold the keys to keeping cancer at
bay, solving the mysteries of auto immune
disease, battling disease, healing wounds and
even easing the aches and pains of aging.
By foresight
and fortunate happenstance, the Department of
Biochemistry and Molecular Biology chaired by
Paul Weigel Ph.D., has achieved a "critical
mass" of faculty glycobiologists ("glyco"
= sugar) just as the relevance of complex
carbohydrates in the development of new
therapies has at last been recognized.
Not that there was much chance that glycobiology
would be considered irrelevant in Weigel's
department. Since coming to the OU college of
medicine a decade ago, with the mandate and
resources to build the department, he's either
hired or trained one of the largest and
best-funded contingents of glycobiologists in
the nation - second in size only to that of the
University of California at San Diego.
First Weigel and then others joined Richard D.
Cummings Ph.D., an internationally recognized
pioneer in the field. Cummings is a George lynn
Cross Research Professor, holder of the Ed
Miller Endowed Chair in Molecular Biology and
self-described "Johnny Appleseed" for spreading
the word about glycomics. Cummings came to OU in
1992.
The "critical mass" of OU glycobiologists and
their army of research assistants have been
responsible for more than 100 patents in the
past decade. Several biotech companies located
at Presbyterian Health Foundation Research Park
have sprung from this research, not to mention
major breakthroughs in identifying some of the
key roles played by carbohydrates.
For example,
Cummings and his research assistant professor,
Tongzhong Ju, M.D., Ph. D., in collaboration
with Lijun Xia, M.D., Ph.D., and Roger EcEver,
MD., at the Oklahoma Medical Research
Foundation, found that mice engineered to lack
the T-synthases gene are unable to grow new
blood vessels through the process called
angiogenesis. This was the first know indication
that the addition of sugars to proteins
regulated such fundamental process as
angiogenesis. It stimulated enormous excitement
at the prospect of finding a way to keep
cancerous tumors from causing formation of blood
vessels that sustain their growth.
In another first, Cummings and Ju discovered
that some tumor cells carry a mutation with a
gene that regulates the creation of
glycoproteins, which, in turn, regulate cell
growth. Cummings speculates that this gene,
which he an Ju have dubbed Cosmic, mutates
spontaneously early in the life of the tumor.
The mutation
of the Cosmc gene leads to altered glycoproteins
possibly improved survivability of cancer cells
and even the enhanced ability to metastasize.
These altered
carbohydrate structures have been found in
breast, colon, gastric, ovarian and liver
cancer.
In 1999, Cummings, Weigel, their faculty
colleagues and several others outside the
department - "those of us excited and interested
in glycobiology" - funded the Oklahoma Center
for Medical
Glycobiology in the Stantion L. Young
Biomedical Research Center building on campus.
Cummings is the center's director.
Their goals
for promoting research in this
under-appreciated field of science were
ambitious. They wanted to be able to provide
technical assistance to all researchers in the
field, foster professional collaborations and
respond to request for help from any clinical or
scientist who wanted to know more.
They also wanted to be among those who would
move the field forward.
"Paul Weigel and I decided that through this
center, we'd be able to complete with the giant
universities and research institutions like MIT
and Scripps Research Institute, "Cummings
recalls. They were right.
With
sophisticated equipment purchased with grants
form the Presbyterian Health Foundation and
funding obtained by the growing glycobiology
faculty, the center found itself perfectly
placed in the fall of 2001 when the National
Institutes of Health pledged $34 million
over five years to help scientists understand
the role of interactions between carbohydrates
and proteins in cell-to-cell communication.
This NIH "glue grant" project is called the
Consortium for Functional Glycomics. Because
progress in determining the functions of
carbohydrates has been slow, the consortium
promised to change that by bringing together a
large group of scientist from leading academic
medical centers across the country.
Cummings is a member of the consortium steering
committee, and the Oklahoma Center for Medical
Glycobiology is home to two of the seven "core"
laboratories participating in the consortium.
(see below)
AT THE CORE
The OU
College of Medicine is home to two of the seven
labs participating in the NIH-Funded efforts to
identify the millions of carbohydrate structures
in the human body and discover their functions.
The Core C sequencing lab uses mass spectrometry
and other methods to reveal the structure and
chemical properties of carbohydrate molecules
for the various animal tissues in which they are
found. OU researchers share this task with
scientists at the Imperial College of London.
Mass spectrometry allows scientists to detect
compounds at unimaginably minute levels.
In Core H, researcher dot what's called a "glycan
array" with little "spots" of identified
carbohydrate structures. This array of spots is
incubated with extracts of human or animal
tissue or purified proteins to identify the
carbohydrate binding proteins and determine
which carbohydrate compounds they recognize.
Using this technique, Core H identifies samples
for scientist around the world.
The work is an exciting as it is daunting. As
Cummings says with barely contained delight, "We
haven't even found the tip of the iceberg."
MIT calls
glycomics one of the 10 emerging technologies
"that will change the world."
Weigel, a George Lynn Cross Research Professor,
has been working for decades to ferret out the
role of complex carbohydrates.
He says
there's a "straightforward" reason why science
is suddenly so interested in these molecules,
and it has everything to do with the dawning
realization of their biomedical importance. "All
but one of the molecules that are outside the
cell contain carbohydrates, whether there in
blood, the lymph, the matrix, stuck between
cells or on the surface of cells. Every protein
with potential for therapeutic use whether it's
a hormone or an antibody, is a glycoprotein", he
says.
"The hold-up has been that it's technically
much, much more difficult to study carbohydrate
structures than to study proteins or DNA,"
Weigel said. Unlike proteins which are produced
by an individual gene and are linear in
structure, carbohydrates form intricate three
dimensional structures from a cascade of
chemical instructions.
"Of we could figure out all the (sugar)
structures in my body and your body, then at
least we'd have a library, just as we now know
all of the genes in a genome. We'd be able to
ask, 'What does this one do?' 'Where is it?' Is
it important?' 'Is it involved in cancer?' 'Is
it involved in something that is bad in terms of
blood vessels, for example?"
Teasing out the answers isn't easy for a number
of reasons. Sugar molecules combine, branch and
dangle in a seemingly infinite number of ways,
making cataloging the shape alone a daunting
task. There is also the challenge of identifying
those proteins that "turn on" the production of
all these structures and the ones that turn them
off.
Once sugar structures are identified, "you can
start to ask what they are and what they are
doing.," Weigel said.
Weigel has
been asking these questions for years, and
lately in collaboration with faculty colleague
Paul DeAngelis Ph.D., has made some significant
breakthroughs. These discoveries involve some
very complex sugar structures and some very tiny
bugs in making life easier for Baby Boomers
and for everyone who undergoes surgery.
The first
sugar structure is the polymer Hyaluronic acid
(or HA), a viscous substance that lubricates
your joints and keep your eyeballs full and
round. The second is heparin, an anticoagulant
whose use is ubiquitous in modern hospitals.
Third is chondroitin, important for fighting
osteoarthritis. When your body needs any of
these three substance, therapeutics made from
cow and pig parts and even from shark fin are
currently available. However, when
pharmaceutical companies look to new sources,
the bugs and glycobiology enter the picture.
The bugs are certain Streptococcus and
Pasteurella bacteria able to camouflage
themselves with coatings of carbohydrate
molecules. These coatings keep them from being
detected by their hosts' immune system. Weigel
and DeAngelis have discovered enzymes that
catalyze the sugar-building process for HA,
heparin and chondroitin.
The results: bacteria that mass-produce the
three types of sugar chains needed to
manufacture medical devices and therapeutics.
"It's been fun trying to figure out how this
works, "DeAngelis said. "Typically, when the bug
makes molecular camouflage, it's making chains
that are thousands of sugars long."
These long chains and the thousands of
permutations possible in sugar structures are
what make glycobiology such a challenge. They
are also what makes the discoveries in the field
so important.
For example,
long sugar chains of HA are important in eye
surgery, but it now appears that very small
fragments of the NA came make cancer cells
committee apoptosis or suicide. The challenge
has been to coax sugar chains that link up in
the right sizes. The OU scientists have found a
solution. "We've found a way that tames the
catalyst into making small sugar chains that
have anti-cancer activity." DeAngelis
said "it turns out that around 12 to 20 sugars
is the sweet area for making the cancer cell
say, 'Oops, I'm going to commit suicide.'" Using
new mutant versions of the Pasteurella enzyme,
DeAngelis can build molecules one sugar at a
time until the suicide-causing size has been
reached.
"It's an emerging area, but it looks like cancer
cells like having the big' HA (chains) around
because it apparently tells the cell to keep
dividing. But if you put in small sugars, the
signal doesn't occur."
Another recent discovery that new blood vessels
will sprout on instructions from "small" HA is
just another in an endless stream of discoveries
expected to arise as OU biomedical scientist
carve out new territory in the exciting area of
glycobiology.
Note: The options of this article may or may not
be held by the owner of this website.
Glycoproteins nor any other nutritional
component are intended to treat, cure or heal
any ailment or disease condition. We can not be
held responsible for the beliefs expressed by
the authors in the articles on this site.
Thursday, January 27,
2005
Glycomics
- There are 2 Sides to EVERY Story
There are two sides to every
story when it comes to
Glycomics:
Side one - "My
doctor has never hear or told me about this so
it must not be that important!"
Side two - MIT calls glycomics
one of the 10 emerging technologies "that will
change the world."
Which side do you prefer?
Also, Paul Weigel, PhD., from OU
university (University of Oklahoma), a George
Lynn Cross Research Professor, has been working
for decades to ferret out the role of
complex carbohydrates. He says there's a "straightforward"
reason why science is suddenly so interested in
these molecules, and it has everything to do
with the dawning realization of their biomedical
importance.
"All
but one of the molecules that are outside the
cell contain carbohydrates, whether there in
blood, the lymph, the matrix, stuck between
cells or on the surface of cells. Every protein
with potential for therapeutic use whether it's
a hormone or an antibody, is a
glycoprotein", he says.
Now when you read this article
you can decide for yourself how important this
new cutting edge science is to your health and
your wealth.
Best Regards
Ed B. RN MS
Wednesday, January 26,
2005
The New
Nutrition Paradigm
by Rayburne W Goen, MD, FACP, FACC.
December 21, 2001
The New Nutrition and Doubting Doctors
Dear Doctor:
Thank you for allowing me this
opportunity to introduce you to a monumental discovery
in Healthcare, only recently acknowledged (1996) in
Medical Journals and Textbooks.
When I first heard about
Glyconutritients 2-1/2 years ago, I called it
"Hogwash", and declared anyone who claimed that oral
administration of these supplements was of striking
benefit to people suffering from a long list of
unrelated diseases or ailments was a QUACK! In the same
class as all the others making such claims for relief of
a multitude of ailments, whatever the modality, so
blatantly proclaimed and touted in numerous brochures
and catalogs in the daily mail. I was closed-minded--
call it skeptical, dubious, or cynical- as you and the
rest of our Medical profession would have been, and are.
I was, however, receptive enough to read the pertinent
Medical Journals supplied to me, and I must admit I was
a little jarred at the implications of what I read. I
began to look into what turned out to be an overwhelming
amount of related literature:
Carbohydrate Metabolism is suddenly a hot
subject--over 20,000 papers in Medline 1996-1998, and an
equal number since. Most of them are in specialty
Research Journals that we as practicing physicians do
not take or read- nor readily understand! The Clinical
articles published thus far have been mainly
retrospective: case reports of a series of patients with
a major disease, and with suspiciously high percentages
of positive results. I read many of these articles, but
I could not believe they could be documenting something
so fundamentally powerful, as that a mere food
supplement could correct a deficiency in our diet so
vitally important as to be the mechanism of all cellular
communication in our body!
I was already well versed in that kind of
hype! I had previously tried, on myself,
enthusiastically at first, the highly touted Glucosamine,
Chondroitin Sulfate, Cetyl Myristoleate, MSM, SAM-e,
Blue Green Algae, Alfalfa Tea, Olive Leaf Extract,
Colloidal Silver: -- each with lots of “ink” but not one
helped me in any way. I proposed to try
(surreptitiously-“don’t tell anybody”) Glyconutrients
for a list of 21 ailments I could identify in myself,
rated in severity from 1-10, attributable mostly to "old
age" (I was 85 years old at the time). I was not
neurotic-- just trying to be scientific. None of these
completely disabled me, except Arthritis of knees, which
required aspiration of fluid and instillation of a
Cortisone, Depo Medrol, more and more frequently,
eventually about every 3 months for one, then the other
knee.Then I would again be functional; and I had a
Peripheral Neuropathy which impaired my balance and
walking, and sleep because of restless legs. Within 4
months, I became symptom-free of 20 of these 21
complaints: the two mentioned, and a right shoulder
rotator cuff tear, low back pain, cervical disc with
left C-5 radiculopathy, inflammatory osteoarthritis of
hands (I could not shake hands without hurting the next
3 days), hypertension (190/105), hypercholesterolemia
(320mg) since in my 30’s, nocturia 4-6x per night,
urinary urgency incontinence, prostate cancer,
developing cataract left eye, etc. I was able to
discontinue all the 6 prescribed drugs, and all
over-the-counter, except 1 aspirin every other day (I
had a Coronary in 1990, after which I began this). The
drugs had been effective to a degree, but all had side
effects that were either disagreeable or intolerable.
That result was not enough to convince
me. This had to be some sort of “fluke”!
I resolved I could disprove this “stuff”
by persuading a “know-it-all” relative who scoffed at
the idea of taking supplements like these for his
refractory Raynaud's Syndrome (cold-sensitive fingers
that turned purple and agonizingly painful upon
exposure); uncontrolled Diabetes type 2 with serious
adverse effects from Insulin and oral anti-diabetes
drugs; Hypercholesterolemia and Diabetic Peripheral
Neuropathy, worsened by all “statin” drugs for
cholesterol reduction. He was scheduled for replacement
surgery of both knees, each of which had been operated
twice for old injuries and loss of cartilage, poorly
responding to NSAID drugs, and with intolerable side
effects.
He had stated he was going to discontinue
all the above drugs--- he had rather died than live this
miserably. I reminded him that dying is an easy out, but
that he might not die, but be disabled by Heart Attack,
Stroke, Amputations, or Renal failure and Dialysis. I
managed to induce him to try
Glyconutritionals for 4 months, with the assurance
they absolutely could not harm him. He reluctantly
agreed...Three weeks later he reported he was free of
pain and paresthesias, was having normalized blood
sugars on just the one oral anti-diabetes drug he had
continued (but that previously had not controlled the
high blood sugar) His vision and mental clarity were
strikingly improved. He neglected, however, to reorder
the
supplements, and the symptoms all recurred within 2
weeks. Upon resumption of the supplements, the symptoms
again abated. Koch’s postulates fulfilled!!
I still was not convinced! I did
cautiously offer Glyconutrients to several other former
patients, including 2 refractory diabetics with
complications, with similar salutary effects. I was
nearly convinced after almost a year of results that I
could only describe as incredible!
So---- I gave
Glyconutritionals to Zondra, a patient whom I had
“doctored” for 50 years with Muscular Dystrophy, Spinal
Atrophy type. (Her brother had died at age 13 with
Duchenne type MD). She was total care since age 2 years;
unable to do anything for herself; had impairment of
swallowing; and was on Oxygen 24 hours daily. She was
able to do some ceramics painting, with her right arm
supported on a table, for 2 hours, twice a week. 4
months after starting
glyconutrients, she could, for the first time in 50
years, feed herself, brush her teeth, scratch her nose,
and is now off Oxygen for 3-4 hours daily. She can now
swallow well, and she can paint 6-8 hours per day, 6
days a week! She states “I have so much energy I could
do more, but know I should rest some, whether I feel the
need or not!” She has sustained this improvement, and
for the first time ever she has not been treated or
hospitalized for respiratory failure or infection in
over a year, despite a Flu epidemic disabling two of her
Nurses and her room mate!
Bill, a former Surgical Technician in the
Service, developed Type 2 Diabetes after returning from
overseas in the 80’s. When originally diagnosed, his
blood sugars were in the 900’s and remained
uncontrollably high (above 500) for many years, despite
multiple injections of regular Insulin up to 200 units
daily, plus Ultra-Lente (long acting) Insulin 120 Units
daily. He exhibited Retinopathy, with bleeding inside
both eyes requiring years of Laser cautery therapy every
3 months, which provided some improvement but could not
prevent subsequent recurrences. He developed Peripheral
Neuropathy of both legs and arms with complications of
Diabetic Ulcers on his legs and feet, for which
amputation was advised. This he refused, but searched
the internet to find a possible relief. He experienced
considerable muscle deterioration, with Claudication
(leg cramps) and Angina on attempting to walk half a
block. He gained weight, up to 330 lbs, with the
inactivity. Despite being on multiple anti-hypertension
medications, his blood pressure for years averaged
200/115. He developed arthritis, with difficulty doing
anything with his hands. After 4 years, and requests
from a Podiatrist, his Physical Therapists, a
Neurologist, and a Health South Rehab Doctor, he finally
obtained HMO authorization for an electrified “scooter”
which enabled him to get up and around… In the early
90’s, over a 3-4 months time period, he had a series of
strokes and 3 TIA’s. He was diagnosed Sleep Apnea,
complicated by shortness of breath at rest, necessitating 6 assorted inhalers, including nasal and tracheo-bronchial steroids. He experienced heart failure
with edema of the lower limbs. The strokes left him with
some permanent left-sided weakness, migraine headaches,
and double vision. For years he has been on a
multiplicity of antibiotics - a month without any was
considered a “Good Month”! His Kidneys began to excrete
albumin, and his BUN and Creatinine elevated as he
approached renal failure that would require Dialysis.
Because of the seriousness of his combined health
problems, he “believed this would prove TERMINAL in a
short period of time”. He became severely depressed
because of his condition, and by what it was doing to
his family. Despite what he could find on the Internet,
and despite the efforts of 12 Doctors and Specialists,
nothing seemed able to alter the downward trend of his
health.
He had “given up ALL HOPE, and was making
preparations for his funeral”, when he was introduced to
Glyconutritionals. After some Internet research he
decided as a last resort to try some - “not expecting
“ANYTHING” to happen . After all, nothing else had
helped”. 3 months later the vision was improving, the
ulcers of feet and legs were healed, the pain, swelling,
weakness (including the left side stroke weakness),
shortness of breath, and angina no longer were a
problem.
He was off all 6 inhalers, including
steroids, and his arthritis was all but gone. He is able
to walk without depending on the scooter or a cane. The
Migraine has resolved, as has a chronic sinusitis, and
he has not needed any more antibiotics. Blood pressure
now averages 130/85 The albumin is no longer found in
his urine, and the creatinine levels have not increased,
indicating stable renal function rather than the
previously noted progression. He lost to 280 lbs weight,
and continues to lose fat and regain muscle mass. . The
Insulin has been reduced to 10-50 units daily of
Regular, with Ultra-Lente 60 units each Am and PM . The
blood sugars are running 105-125, and the
Glycohemoglobin (A1c) is now an incredibly low 5.1 (a
measure of the biological level of glucose saturation of
the Red Blood Cells. Very, very good!) He has admittedly
not paid enough attention to his diet, and could no
doubt reduce his weight and Insulin further by following
a low glycemic diet, and, now that he is able, he is
starting to do more exercise. His severe depression is
no more, and best of all, to quote him, “I NOW HAVE
HOPE, WHERE THERE WAS NONE! I am amazed at the changes
that are occurring-some fast, some slow, some not yet,
but things ARE IMPROVING!”
Maxine is a 65 year old housewife who had
Breast Cancer in 1984, treated with bilateral
mastectomy. The cancer recurred in the abdomen and
stomach 13 years later, for which she received 6
chemotherapy treatments in 1997. These were very poorly
tolerated, and did not improve her condition. She
developed obstruction of colon, necessitating a
colostomy; and blockage in the stomach resulting in
abdominal swelling, loss of appetite, and rapid weight
loss. She was told there was nothing more to do, and
Hospice was utilized for pain control with injections of
narcotics, with expectation of death within 6 months. 3
months passed, with a downhill course. She and her
husband did not give up, and sought help from herbs and
whatever anyone might recommend, but without benefit.
Glyconutrients were offered to her, and in
desperation she began to take them. Within 2 weeks she
was out of bed, going to Church, and a week later she
insisted on going to a garage sale! She is now up and
around, doing housework and the cooking, enjoying
eating, in little pain, and the abdominal swelling has
disappeared. Praise God!
Such RESULTS as these, and now many
others, I have not seen before in my 60 years as a
Doctor!! Glyconutrients are fully documented to be safe,
non-toxic, do not interfere with Rx drugs, and they
work! Admittedly, no one thing is 100% - there must yet
be some more unknown essentials, as well as the other
known essentials: oxygen, water, and food: amino acids,
fatty acids, carbohydrates,
vitamins, minerals, trace elements. None of those
are now apparently deficient within our current diet and
traditional supplements - except 6 of the
newly-recognized
8 essential monosaccharides!
The only things that convince most of us
Doctors are CONSISTENT, SAFE, RESULTS. We have all been
led down the primrose path with promising new drugs,
approved by the FDA, and seen them withdrawn from the
market 6 months later because of dire effects on the
liver, kidneys, bone marrow, GI tract, and/or pregnancy.
How many more do we daily prescribe which result in only
occasional "idiosyncratic" lethal effects with approved
doses within the acceptable risk-benefit ratio? (but
over 106,000 in the year 1997 died in hospitals from
reactions to properly prescribed and taken drugs, as
reported in JAMA July 26, 2000. This is the fourth
leading cause of death in the US, outnumbered only by:
Heart Attacks, Cancer, and Diabetes). It has happened in
my practice, as it has in yours and every other Doctor
who prescribes for patients. It has been devastating
enough to me and you, but how much more so to the
patients and their families! For them it is 100%!
Carbohydrates were always acknowledged to
be just for energy. Not any more!! Of the 200 known
simple
saccharides), there are 8 now recognized to be
essential to all cellular function. They are
glucose,
galactose,
mannose,
xylose,
fucose (not fructose),
N-acetylneuraminic acid (also called sialic acid),
N-acetylglucosamine,
N-acetylgalactosamine. Six of these “eight essential
monosaccharides” are universally lacking in our
diet, because of soil depletion, green harvesting,
processing, preservatives, and overcooking. Fortunately
our bodies can make the other 6 from glucose and
galactose, if everything is all right! Obviously,
everything is not all right if the body has a Health
Problem, whether from infections; toxins in our
environment: the air we breathe, the food we eat, the
water we drink; stresses in our lifestyle; deficiency of
a necessary enzyme, vitamin, co-factor, trace mineral;
or a genetic defect, in the 15 or more stages, plus much
energy, to convert one (available) sugar to another!
Currently, the most important one of all these
“essentials” is the one that is missing! And “essential”
means indispensable: without it, the body is
dysfunctional, sick or dying!
There are many new studies, Double-Blind,
Placebo-Controlled, with enough numbers to be
Statistically Significant, as we are so used to seeing,
but these are years away from being reported.
Many are not subject to double blinding
or placebo control, such as near-terminal Cancer cases,
Genetic Disorders with progressive downhill course, and
Immune Dysfunction diseases which are epidemic,
overwhelming us over the past 2-3 decades, and for which
we have no cure --- nor even satisfactory or safe relief
of the symptoms, with our conventional therapy. Asthma,
Lupus, Hepatitis C, Rheumatoid Arthritis,
Osteoarthritis; Cancer, ADD-ADHD, Fibromyalgia, Diabetes
types I and II, Chronic Fatigue Syndrome, Multiple
Sclerosis, AIDS, Ulcerative Colitis, Crohn’s Disease,
Down Syndrome, Muscular Dystrophy , ALS (Lou Gehrig’s
Disease), are just a few examples.
Administration of
Glyconutrients has resulted in improvement or
remission, without any harmful side effects, in each of
these conditions, as documented in reports or
publication in peer-reviewed Medical Journals. What
could possibly be the common denominator of all these?
Immune System Dysfunction! Why? Something is missing!
Glyconutrients are not a treatment, mitigation, or
cure for any disease, but if these food supplements are
supplied in the diet, the body can heal itself of
virtually anything wrong! (But not grow a new tooth in
an adult if one is pulled, nor a new limb if it is
amputated. That is not in our DNA! It is, however, in
the DNA of Earthworms cut in half, Sharks who lose a
tooth, and Centipedes who lose a leg!
These
8 monosaccharides are in and on the surface of every
cell in the body. They are necessary as the
glyco of
glycoproteins on the surface of every cell, as
transmitter or receptor, of all the vital reactions
between cells: defense, repair, regulation, nutrition,
and apoptosis, (the programmed death and recycling of
all cells). Every cell in the body (100 Trillion or so!)
is replaced at different rates: (e.g. WBC, 6-7 days;
RBC's, 3-4 months; DNA and most Internal Organs, 6
months; Bone, 9 months to years; Brain and CNS, 14
months). These monosaccharides are present as a
substrate in the endoplasmic reticulum, and as building
blocks for the glycosolation occurring in the Golgi
apparatus of cells, forming glycoproteins, proteoglycans,
glycolipids, and the N- and O- and GPI- anchored
linkages (Nitrogen- ,Oxygen-, and
Glycosylphosphatidyl-inositol- linkages). This is all
under control of the DNA as the blueprint, and mRNA, as
the message. The glycoproteins translate the messages
and send chemical signals (cytokines) to the appropriate
receptors, (also glycoproteins) to facilitate the proper
action at the cellular level. This is the Universal Code
of Life, equivalent to the Microsoft Operating System,
which runs all computers! This is extremely complicated
and has to be, not 99.9999% perfect, but 100%, or there
is dysfunction, disease, or death! I have studied it
intensively, still know so little, but yet enough to be
awed and excited by what I have witnessed! Supplying
Glyconutritionals in the diet has enabled the body to
modulate the immune system: elevate those elements that
are too low, as in Cancer and AIDS; reduce those that
are too high, as in autoimmune diseases; or do both, as
in most of the immune dysfunctions!!
This Modulation had been considered
impossible-something never before seen in Medicine. The
Natural Killer Cells, necessary as the first line of
defense against Infection and Cancer, are reduced by 30
% in even the “normal” population in the past 2 decades,
and are further falling by 3% per year. No wonder
250,000,000 of the US population are suffering from some
form of acute or chronic disease! These NKcells are
restored to normal numbers in those receiving
Glyconutrients. How? I do not know! But the body knows!
Thank God!
Dr. Robert K Murray, Senior Editor of
Harper's Biochemistry (Appleton and Lange,1996) wrote
the chapters 56 through 65 on: Glycoproteins; The 8
Essential Monosaccharides; The Extracellular Matrix;
Muscle Metabolism; The Immune System; etc. I now have
the 2001 revision, and am poring over the awesome
biochemical reactions, newly-discovered, in this
explosively growing segment of Biochemistry:
Glycoscience,
Glycobiology, and
Glycomics! I will ask you, Doctor, if I may, "How
did you advertise when you started your Medical
Practice? Newspaper? Radio? TV?" "Or Word of Mouth from
satisfied Patients?? I can guess!!! So did I! Don't
knock Word of Mouth! We do not sell products, but
educate and introduce the good news to those we love and
want to help, who then can order these Glyconutrients
wholesale from the only company who can supply all of
them, have them shipped directly to their home; to be
taken as a complement to conventional Medical Care. We
and they see benefits more safely, more completely, more
consistently, and less expensively, than we have ever
seen in our lives before! And they, in turn, will share
the good news with others who are suffering from the
effects of these deficiencies!
I am now retired, but I can’t deny my
love for Medicine, nor yet ignore the recent monumental
advancements in the Science of Nutrition, and especially
the role of monosaccharides in the formation of
glycoproteins, so vital in the function of the cells of
our body. At age 87 I am starting a new career (nay,
Mission!) to share with everyone I meet, this epochal
Nutritional Breakthrough, and its effect on the immune
function. Medicine has advanced beyond the
Blood-letting, Leeches, and Maggots treatment of disease
to Immunizations, Wonder Drugs, incredible Surgery,
Organ Transplants, and Genomes. We have great
expectations from the latter, but the promised wondrous
cures are yet years away from application, and even the
initial Genetic modifications are fraught with the same
old side-effect complications as other synthetics have
exhibited. The body is programmed by God to utilize
whatever it needs from our diet, and is not about to
change. Stem Cell Cloning is far from perfect, although
it must be invariably perfect, and subject to the same
responses to nutritional deficiencies as those we have
found so refractory-until the missing Glyconutrients are
supplied. Glyconutrients are already available here and
now, safe and effective, awaiting but the eventual
universal recognition by all Health Professionals: that
this New Nutrition is the Keystone of Prevention and
Wellness, as our New Focus in the Practice of Medicine,
versus the traditional paradigm of Treating Sickness
with Drugs).
This new Paradigm in Medicine did not
originate in the traditional “A Drug Cure for Every
Disease” concept of Pharmacology, nor yet by the
Nutritionists. This is a “Disruptive Technology”,
comparable to the displacement of wax and vinyl
phonograph records with magnetic tape, and this in turn
by digital CD, each of which was birthed by a totally
unrelated industry. Likewise, was the obsolescence of
the watch and clock by the quartz crystal; and the
mechanical typewriter by the electric, and this, in
turn, by the word processor of the computer, again an
upstart industry.
The new Biochemistry: Glycobiology,
Glycoscience, Glycomics: Glyconutrients!
For those who might be interested in my
“pedigree”, I have BA and MD degrees (1939) University
of Colorado: (Phi Beta Kappa, and Alpha Omega Alpha,
Honor Medical Society). Lt. Col. Medical Corps. Army of
US, WW II; Diplomate American Board of Internal
Medicine; Fellow American College of Physicians (FACP);
Fellow American of College Cardiology (FACC); Clinical
Associate Professor of Medicine, University of Oklahoma
School of Medicine, Tulsa; Past Chairman Medical
Section, St John Medical Center and of St. Francis
Hospital; past Vice-President Medical Staff St. John
Hospital; past President Medical Staff St. Francis
Hospital.
I couldn’t blame you if you thought me a
Kook,--- but do please be open-minded, for your own
sake, and for that of all your patients. And in so doing
you will honor the aphorism of that wise old Doctor,
Hippocrates, the Father of Medicine, whose first concern
with his patients was “Primum non nocere.” Above all, do
no harm! And his next was “Let your food be your
medicine, and let your Medicine be your food.”
What goes around comes around!
Rayburne W. Goen, Sr. MD
Note: These saccharides are not intended
to heal, treat, or cure any disease.
Tuesday, January 25, 2005
Note: Glyconutrients
are not intended to heal, treat, or cure any disease.
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